The Value of Nuclear Medicine and Molecular Imaging

Molecular Imaging: Making a Difference

Library of Clinical Applications in 18F FDG PET CT

Please click the image above to reach the full library of clinical applications in PET CT

The Clinical Applications are arranged as follows:

1. Bone and Soft Tissue Sarcoma 
2. Breast Cancer Imaging with 18F FDG PET CT
3. Cancer of Unknown Origin
4. Central Nervous System Tumors
5. Colorectal Carcinomas
6. Gastric Carcinoma
7. Gastrointestinal Stromal Tumor
8. Germinal
9. Gynaecological
10. Head and Neck
11. Hepatobiliary
12. Lung
13. Lymphoma
14. Melanoma
15. Nasopharyngeal
16. Oesophagus
17. Other Malignancies-Multiple Myeloma
18. Pancreas
19. Pleural
20. Thyroid
21. Urinary Tract

By clicking the image the link the page is redirected to the IAEA teaching web site on each of the above mentioned. Each type of carcinoma is labelled as Staging / Restaging / Treatment Response / Therapy Planning. Each of the sections where case studies are presented are marked with bullets, clicking each bullet will lead you to the PDf teaching file on each specific topic or carcinoma. Or Click the link here. 

Ovarian and Endometrial Uptake in 18F FDG PET CT

http://nucleus.iaea.org/HHW/NuclearMedicine/PET_CT_Gallery/FDG_Biodistribution/2._Normal_Variants/5._Ovarian_and_Endometrium.pdf

Ovarian and Endometrial uptake in 18F FDG PET CT is common and dependent on the time of imaging with relation to the menstrual cycle. These findings should be interpreted carefully. 

Click the above links for full description from the IAEA Teaching files site of the Human Health Campus. 

Thymus 18F FDG Uptake - Normal Variant or Hyper- stimulation

http://nucleus.iaea.org/HHW/NuclearMedicine/PET_CT_Gallery/FDG_Biodistribution/2._Normal_Variants/6._Thymus.pdf

The above image shows the standard normal biodistribution of 18F FDG uptake in a patient imaged with 18 F FDG.

Please click on the image or link above to view the PDF of teaching files on increased thymus uptake which can happen as a normal Variant due to hyper-stimulation of thymus post chemotherapy. This could be misinterpreted as active disease in many a situation.    

Normal Bio-distribution of 18F FDG Imaging in PET CT

Click on Image to link to IAEA official website for detailed description of 18F FDG - PET CT Bio-distribution  

The Role of PET/CT in Radiation Treatment Planning for Cancer Patient Treatment

Please Click the above image to download the TEC DOC from the official IAEA site

Clinical PET, combined with utilization of 18F-FDG, may have an important role in radiation treatment planning (RTP) in lung cancer. In addition to determining if RT is appropriate and whether therapy will be given with curative or palliative intent, 18F-FDG-PET is useful for determining therapy ports. It can be used both to limit ports to spare normal tissue and to include additional involved regions. Several studies have shown that PET has an impact on RTP in an important proportion of patients. It is to be hoped that treatment plans that include all the 18F-FDG-avid lesions or the 18F-FDG-avid portions of a complex mass will result in more effective local control with less unnecessary tissue being treated.

The IAEA has placed emphasis on the issue of application of clinical PET for radiation treatment planning in various cancer patients.